The Order of Saints Maurice and Lazarus is a Roman Catholic dynastic order of knighthood bestowed by the royal House of Savoy. It is the second-oldest order of knighthood in the world, tracing its lineage to AD 1098, and it is one of the rare orders of knighthood recognized by papal bull, in this case by Pope Gregory XIII. In that bull, Pope Gregory XIII bestowed upon Emmanuel Philibert, Duke of Savoy and his Savoy successors, the right to confer this knighthood in perpetuity. The Grand Master is Prince Emanuele Filiberto of Savoy, Prince of Venice, also known as the Duke of Savoy, the grandson of the last King of Italy, Umberto II. However, Emanuele Filiberto's cousin twice removed Prince Aimone, Duke of Aosta claims to be grand master as his father claimed to be head of the house of Savoy.

The House of Savoy is an Italian royal house that was established in 1003 in the historical Savoy region. Through gradual expansion, the family grew in power from ruling a small Alpine county north-west of Italy to absolute rule of the Kingdom of Sicily from 1713 to 1720, when they were handed the island of Sardinia, over which they would exercise direct rule from then onward.