Orontes I was a military officer of the Achaemenid Empire and satrap of the Armenia at the end of the 5th-century BC and first half of the 4th-century BC. He is notable for having led the unsuccessful Great Satraps' Revolt in Asia Minor against the Achaemenids from 362/1 BC to 360/359 BC.

The Great Satraps' Revolt, or the Revolts of the Satraps, was a rebellion in the Achaemenid Empire of several satraps in western Anatolia against the authority of the Great King Artaxerxes II. The Satraps who revolted were Datames, Ariobarzanes, Orontes, Autophradates, and Mausolus. The timing of their revolts varied, as did the circumstances that induced them to rebel. Though often portrayed as a general uprising, there was little coordination among them and at no time did they actually threaten Artaxerxes directly. Their efforts were aimed at secession rather than a takeover of the Empire.