The Pan-American Highway is a network of roads stretching across the Americas, measuring about 30,000 kilometres (19,000 mi) in total length. Except for a break of approximately 100 km (60 mi) across the border between Colombia and Panama, the roads link most of the Pacific coastal countries of North America and South America in a connected highway system. According to Guinness World Records, the Pan-American Highway is the world's longest "motorable road".

Panama, officially the Republic of Panama, is a country in Latin America at the southern end of Central America, bordering South America. It is bordered by Costa Rica to the west, Colombia to the southeast, the Caribbean Sea to the north, and the Pacific Ocean to the south. Its capital and largest city is Panama City, whose metropolitan area is home to nearly half the country's over 4 million inhabitants.