Panic in the Streets is a 1950 American film noir medical drama / thriller, directed by Elia Kazan. released by 20th Century Fox studios in Hollywood, Los Angeles, California. It was shot exclusively on location in New Orleans, Louisiana, and features numerous scenes around the city and Port of New Orleans along the Mississippi River and showing various New Orleans citizens in speaking and non-speaking roles.

Elias Kazantzoglou, known as Elia Kazan, was an American film and theatre director, producer, screenwriter and actor, described by The New York Times as "one of the most honored and influential directors in Broadway and Hollywood history".