Dominicans are an ethno-national people, a people of shared ancestry and culture, who have ancestral roots in the Dominican Republic. The Dominican ethnic group was born out of a fusion of European, native Taino, and African elements, which is an ethnic fusion that goes back to the 16th century. Due to this fusion, the majority of Dominicans are of mixed-race heritage, tracing roots mainly to these three sources with the vast majority being of predominant African ancestry. The demonym Dominican can be traced as far back as the 1621. The name came from Santo Domingo, which was not only the name of the capital city but also of the entire island at the time, Spain used this term to refer to the inhabitants of Spanish province of Santo Domingo. Recent immigrants and their children, who are legal citizens of the Dominican Republic, can be considered "Dominican" by nationality but not ethnicity due to not having ancestral roots in the country.

The Captaincy General of Santo Domingo was the first Capitancy in the New World, established by Spain in 1492 on the island of Hispaniola. The Capitancy, under the jurisdiction of the Real Audiencia of Santo Domingo, was granted administrative powers over the Spanish possessions in the Caribbean and most of its mainland coasts, making Santo Domingo the principal political entity of the early colonial period.