This is a list of prime ministers of Madagascar, since the establishment of the office of chief minister in 1828, during the Merina Kingdom.

The Kingdom of Merina, or Kingdom of Madagascar, officially the Kingdom of Imerina, was a pre-colonial state off the coast of Southeast Africa that, by the 18th century, dominated most of what is now Madagascar. It spread outward from Imerina, the Central Highlands region primarily inhabited by the Merina ethnic group with a spiritual capital at Ambohimanga and a political capital 24 km (15 mi) west at Antananarivo, currently the seat of government for the modern state of Madagascar. The Merina kings and queens who ruled over greater Madagascar in the 19th century were the descendants of a long line of hereditary Merina royalty originating with Andriamanelo, who is traditionally credited with founding Imerina in 1540.