Randolph County is a county on the central eastern border of the U.S. state of Alabama. As of the 2020 census, the population was 21,967. Its county seat is Wedowee. Its name is in honor of John Randolph, a member of the United States Senate from Virginia. Randolph County was a prohibition or dry county until 2012, when the citizens of Randolph County voted to repeal prohibition.

Wedowee is a town in Randolph County, Alabama, United States. At the 2010 census the population was 823, up from 818 in 2000. The small town is the county seat of Randolph County. It was initially incorporated in 1836, but its charter lapsed by the late 19th century. It was reincorporated in 1901.