The Rhine–Main–Danube Canal, is a canal in Bavaria, Germany. Connecting the Main and the Danube rivers across the European Watershed, it runs from Bamberg via Nuremberg to Kelheim. The canal connects the North Sea and Atlantic Ocean to the Black Sea, providing a navigable artery between the Rhine delta, and the Danube Delta in south-eastern Romania and south-western Ukraine. The present canal was completed in 1992 and is 171 kilometres (106 mi) long.

The Main is the longest tributary of the Rhine. It rises as the White Main in the Fichtel Mountains of northeastern Bavaria and flows west through central Germany for 525 kilometres (326 mi) to meet the Rhine below Rüsselsheim, Hesse. The cities of Mainz and Wiesbaden are close to the confluence.