The River Crane, a tributary of the River Thames, runs 8.5 miles (13.6 km) in West London, England. It forms the lower course of Yeading Brook. It adjoins or passes through three London boroughs: Hillingdon, Hounslow and Richmond upon Thames, in the historic county of Middlesex. The drainage basin is heavily urbanised but many of the Hayes to Whitton flood-meadows have been conserved, forming a narrow, green vale, opening out to what remains of Hounslow Heath in the centre – a near-continuous belt of semi-natural habitat.

Yeading Brook is the dominant source of the River Crane, in outer North West then West London. The western branch flows 25.8 km (16.0 mi) south. It rises in the far south of suburban Pinner and drains all of the western suburbs of Harrow, insofar as they have not been by historical practice connected into sewers.