The Royal Governor of Chile ruled over the Spanish colonial administrative district called the Captaincy General of Chile, and as a result the Royal Governor also held the title of a Captain General. There were 66 such governors or captains during the Spanish conquest and the later periods of Spanish-centered colonialism. Since the first Spanish–Mapuche parliaments in the 17th century it became an almost mandatory tradition for each governor to arrange a parliament with the Mapuches.

The General Captaincy of Chile, Governorate of Chile, or Kingdom of Chile, was a territory of the Spanish Empire from 1541 to 1818 that was, initially, part of the Viceroyalty of Peru. It comprised most of modern-day Chile and southern parts of Argentina in the Patagonia region. Its capital was Santiago de Chile. In 1810 it declared itself independent, with the Spanish reconquering the territory in 1814, but in 1818 it gained independence as the Republic of Chile. It had a number of Spanish governors over its long history and several kings.