STS-101 was a Space Shuttle mission to the International Space Station (ISS) flown by Space Shuttle Atlantis. The mission was a 10-day mission conducted between 19 May 2000 and 29 May 2000. The mission was designated 2A.2a and was a resupply mission to the International Space Station. STS-101 was delayed 3 times in April due to high winds. STS-101 traveled 4.1 million miles and completed 155 revolutions of the earth and landed on runway 15 at Kennedy Space Center. The mission was the first to fly with a glass cockpit.

Space Shuttle Atlantis is a retired Space Shuttle orbiter vehicle which belongs to NASA, the spaceflight and space exploration agency of the United States. Atlantis was manufactured by the Rockwell International company in Southern California and was delivered to the Kennedy Space Center in Eastern Florida in April 1985. Atlantis is also the fourth operational and the second-to-last Space Shuttle built. Its maiden flight was STS-51-J made from October 3 to 7, 1985.