STS-37, the thirty-ninth NASA Space Shuttle mission and the eighth flight of the Space Shuttle Atlantis, was a six-day mission with the primary objective of launching the Compton Gamma Ray Observatory (CGRO), the second of the Great Observatories program which included the visible-spectrum Hubble Space Telescope (HST), the Chandra X-ray Observatory (CXO) and the infrared Spitzer Space Telescope. The mission also featured two spacewalks, the first since 1985.

The National Aeronautics and Space Administration is an independent agency of the U.S. federal government responsible for the civil space program, aeronautics research, and space research. Established in 1958, it succeeded the National Advisory Committee for Aeronautics (NACA) to give the U.S. space development effort a distinct civilian orientation, emphasizing peaceful applications in space science. It has since led most of America's space exploration programs, including Project Mercury, Project Gemini, the 1968–1972 Apollo Moon landing missions, the Skylab space station, and the Space Shuttle. Currently, NASA supports the International Space Station along with the Commercial Crew Program, and oversees the development of the Orion spacecraft and the Space Launch System for the lunar Artemis program.