Sam Mitchell is a fictional character from the BBC soap opera EastEnders. The third member of the Mitchell family to appear on the soap, Sam was introduced as a 15-year-old schoolgirl in July 1990, originally played by Danniella Westbrook. Westbrook quit in 1993, but Sam reappeared from 1995 to 1996 and from 1999 to 2000. In both stints, Sam was written out earlier than the producers intended due to off-screen controversies surrounding Westbrook. In January 2002, Sam was introduced for a fourth time, but the role was recast to Kim Medcalf, who stayed in the role until November 2005. Diederick Santer later decided to reintroduce Sam for a brief stint in 2009 and opted to bring Westbrook back. Westbrook briefly reprised the role once again in 2016 for the funeral of Sam's mother Peggy Mitchell. In January 2022, it was announced that Sam would be returning to the show, this time played by Medcalf again. Medcalf’s return scenes aired on 18 April 2022. Medcalf took an extended break from the show in 2023, with Sam departing on 13 April 2023 and returning seven months later on 21 November 2023. On 18 January 2024, Sam made an unannounced departure from the show following Medcalf's decision to leave indefinitely.

Kim Louise Medcalf is an English actress and singer. She is best known for portraying the role of Sam Mitchell in the BBC soap opera EastEnders.