The San Francisco Transbay Terminal was a transportation complex in San Francisco, California, United States, roughly in the center of the rectangle bounded north–south by Mission Street and Howard Street, and east–west by Beale Street and 2nd Street in the South of Market area of the city. It opened on January 14, 1939 as a train station and was converted into a bus depot in 1959. The terminal mainly served San Francisco's downtown and Financial District, as transportation from surrounding communities of the Bay Area terminated there such as: Golden Gate Transit buses from Marin County, AC Transit buses from the East Bay, and SamTrans buses from San Mateo County. Long-distance buses from beyond the Bay Area such as Greyhound and Amtrak Thruway also served the terminal. Several bus lines of the San Francisco Municipal Railway connected with the terminal.

Mission Street is a north-south arterial thoroughfare in Daly City and San Francisco, California that runs from Daly City's southern border to San Francisco's northeast waterfront. The street and San Francisco's Mission District through which it runs were named for the Spanish Mission Dolores, several blocks away from the modern route. Only the southern half is historically part of El Camino Real, which connected the missions. Part of Mission Street in Daly City is signed as part of State Route 82.