Santa Cruz Province is a province of Argentina, located in the southern part of the country, in Patagonia. It borders Chubut Province to the north, and Chile to the west and south, with an Atlantic coast on its east. Santa Cruz is the second-largest province of the country, and the least densely populated in mainland Argentina.

Patagonia is a geographical region that encompasses the southern end of South America, governed by Argentina and Chile. The region comprises the southern section of the Andes Mountains with lakes, fjords, temperate rainforests, and glaciers in the west and deserts, tablelands, and steppes to the east. Patagonia is bounded by the Pacific Ocean on the west, the Atlantic Ocean to the east, and many bodies of water that connect them, such as the Strait of Magellan, the Beagle Channel, and the Drake Passage to the south.