Sepulveda Boulevard is a major street and transportation corridor in the City of Los Angeles and several other cities in western Los Angeles County, California. The street parallels Interstate 405 for much of its route. Portions of Sepulveda Boulevard between Manhattan Beach and Los Angeles International Airport (LAX) are designated as part of State Route 1.

Los Angeles, often referred to by its initials L.A., is the most populous city in the U.S. state of California. With roughly 3.9 million residents within the city limits as of 2020, Los Angeles is the second-most populous city in the United States, behind only New York City; it is also the commercial, financial and cultural center of Southern California. Los Angeles has an ethnically and culturally diverse population, and is the principal city of a metropolitan area of 13.2 million people. Greater Los Angeles, which includes the Los Angeles and Riverside–San Bernardino metropolitan areas, is a sprawling metropolis of over 18 million residents.