Serpens is a constellation in the northern celestial hemisphere. One of the 48 constellations listed by the 2nd-century astronomer Ptolemy, it remains one of the 88 modern constellations designated by the International Astronomical Union. It is unique among the modern constellations in being split into two non-contiguous parts, Serpens Caput to the west and Serpens Cauda to the east. Between these two halves lies the constellation of Ophiuchus, the "Serpent-Bearer". In figurative representations, the body of the serpent is represented as passing behind Ophiuchus between Mu Serpentis in Serpens Caput and Nu Serpentis in Serpens Cauda.

The Eagle Nebula is a young open cluster of stars in the constellation Serpens, discovered by Jean-Philippe de Cheseaux in 1745–46. Both the "Eagle" and the "Star Queen" refer to visual impressions of the dark silhouette near the center of the nebula, an area made famous as the "Pillars of Creation" imaged by the Hubble Space Telescope. The nebula contains several active star-forming gas and dust regions, including the aforementioned Pillars of Creation. The Eagle Nebula lies in the Sagittarius Arm of the Milky Way.