The Seven Seals of God from the Bible's Book of Revelation are the seven symbolic seals that secure the book or scroll that John of Patmos saw in an apocalyptic vision. The opening of the seals of the document occurs in Rev Ch 5–8 and marks the Second Coming of the Christ and the beginning of The Apocalypse/Revelation. Upon the Lamb of God/Lion of Judah opening a seal on the cover of the book/scroll, a judgment is released or an apocalyptic event occurs. The opening of the first four Seals releases the Four Horsemen, each with his own specific mission. The opening of the fifth Seal releases the cries of martyrs for the "Word/Wrath of God". The sixth Seal prompts plagues, storms and other cataclysmic events. The seventh Seal cues seven angelic trumpeters who in turn cue the seven bowl judgments and more cataclysmic events.

Lamb of God is a title for Jesus that appears in the Gospel of John. It appears at John 1:29, where John the Baptist sees Jesus and exclaims, "Behold the Lamb of God who takes away the sin of the world." It appears again in John 1:36.