Shaftesbury Avenue is a major road in the West End of London, named after The 7th Earl of Shaftesbury. It runs north-easterly from Piccadilly Circus to New Oxford Street, crossing Charing Cross Road at Cambridge Circus. From Piccadilly Circus to Cambridge Circus, it is in the City of Westminster, and from Cambridge Circus to New Oxford Street, it is in the London Borough of Camden.

The West End of London is a district of Central London, London, England, west of the City of London and north of the River Thames, in which many of the city's major tourist attractions, shops, businesses, government buildings and entertainment venues, including West End theatres, are concentrated.