From the 1960s to the 1990s, South Africa pursued research into weapons of mass destruction, including nuclear, biological, and chemical weapons under the apartheid government. South Africa’s nuclear weapons doctrine was designed for political leverage rather than actual battlefield use, specifically to induce the United States of America to intervene in any regional conflicts between South Africa and the Soviet Union or its proxies. To achieve a minimum credible deterrence, a total of six nuclear weapons were covertly assembled by the late 1980s.

A weapon of mass destruction (WMD) is a biological, chemical, radiological, nuclear, or any other weapon that can kill or significantly harm many people or cause great damage to artificial structures, natural structures, or the biosphere. The scope and usage of the term has evolved and been disputed, often signifying more politically than technically. Originally coined in reference to aerial bombing with chemical explosives during World War II, it has later come to refer to large-scale weaponry of warfare-related technologies, such as biological, chemical, radiological, or nuclear warfare.