Southampton Terminus railway station served the Port of Southampton and Southampton City Centre, England from 1839 until 1966. The station was authorised on 25 July 1834 and built as the terminus of the London and Southampton Railway, which later changed its name to the London and South Western Railway (LSWR). The station opened as "Southampton" on 10 June 1839, although it was not officially operational until 11 May 1840, due to the track not being fully linked between Winchester and Basingstoke.

The London and Southampton Railway was an early 4 ft 8+1⁄2 in standard gauge railway company between London and Southampton, in England. It opened in stages from 1838 to 1840 after a difficult construction period, but was commercially successful.