The Souvenir Henri Desgrange is an award and cash prize given in the yearly running of the Tour de France, one of cycling's Grand Tour races. It is won by the rider that crosses a particular point in the race, mostly the summits of the highest and iconic climbs in the Alps and Pyrenees. It is named in honour of the creator and first race director of the Tour, French sports journalist Henri Desgrange, who was passionate about taking the Tour de France as high up in the mountains as possible using the most difficult routes.

Henri Desgrange was a French bicycle racer and sports journalist. He set twelve world track cycling records, including the hour record of 35.325 kilometres (21.950 mi) on 11 May 1893. He was the first organiser of the Tour de France.