The Soyuz MS is a revision of the Russian spacecraft series Soyuz first launched in 2016. It is an evolution of the Soyuz TMA-M spacecraft, with modernization mostly concentrated on the communications and navigation subsystems. It is used by Roscosmos for human spaceflight. The Soyuz MS has minimal external changes with respect to the Soyuz TMA-M, mostly limited to antennas and sensors, as well as the thruster placement.

Soyuz is a series of spacecraft which has been in service since the 1960s, having made more than 140 flights. It was designed for the Soviet space program by the Korolev Design Bureau. The Soyuz succeeded the Voskhod spacecraft and was originally built as part of the Soviet crewed lunar programs. It is launched on a Soyuz rocket from the Baikonur Cosmodrome in Kazakhstan. Between the 2011 retirement of the Space Shuttle and the 2020 demo flight of SpaceX Crew Dragon, the Soyuz served as the only means to ferry crew to or from the International Space Station, for which it remains heavily used. Although China did launch crewed Shenzhou flights during this time, none of them docked with the ISS.