The retirement of NASA's Space Shuttle fleet took place from March to July 2011. Discovery was the first of the three active Space Shuttles to be retired, completing its final mission on March 9, 2011; Endeavour did so on June 1. The final shuttle mission was completed with the landing of Atlantis on July 21, 2011, closing the 30-year Space Shuttle program.

Space Shuttle Endeavour is a retired orbiter from NASA's Space Shuttle program and the fifth and final operational Shuttle built. It embarked on its first mission, STS-49, in May 1992 and its 25th and final mission, STS-134, in May 2011. STS-134 was expected to be the final mission of the Space Shuttle program, but with the authorization of STS-135 by the United States Congress, Atlantis became the last shuttle to fly.