The Spanish Missions in Texas comprise a series of religious outposts established by Spanish Catholic Dominicans, Jesuits, and Franciscans to spread the Catholic doctrine among area Native Americans, but with the added benefit of giving Spain a toehold in the frontier land. The missions introduced European livestock, fruits, vegetables, and industry into the Texas area. In addition to the presidio and pueblo (town), the misión was one of the three major agencies employed by the Spanish crown to extend its borders and consolidate its colonial territories. In all, twenty-six missions were maintained for different lengths of time within the future boundaries of the state of Texas.

Texas is the most populous state in the South Central region of the United States. It borders Louisiana to the east, Arkansas to the northeast, Oklahoma to the north, New Mexico to the west, and the Mexican states of Chihuahua, Coahuila, Nuevo León, and Tamaulipas to the south and southwest. Texas has a coastline on the Gulf of Mexico to the southeast. Covering 268,596 square miles (695,660 km2), and with over 30 million residents as of 2023, it is the second-largest U.S. state by both area and population.