Spica is the brightest object in the constellation of Virgo and one of the 20 brightest stars in the night sky. It has the Bayer designation α Virginis, which is Latinised to Alpha Virginis and abbreviated Alpha Vir or α Vir. Analysis of its parallax shows that it is located 250±10 light-years from the Sun. It is a spectroscopic binary star and rotating ellipsoidal variable; a system whose two stars are so close together they are egg-shaped rather than spherical, and can only be separated by their spectra. The primary is a blue giant and a variable star of the Beta Cephei type.

Virgo is one of the constellations of the zodiac. Its name is Latin for maiden, and its old astronomical symbol is . Between Leo to the west and Libra to the east, it is the second-largest constellation in the sky and the largest constellation in the zodiac. The ecliptic intersects the celestial equator within this constellation and Pisces. Underlying these technical two definitions, the sun passes directly overhead of the equator, within this constellation, at the September equinox. Virgo can be easily found through its brightest star, Spica.