Stanton County is a county located in the U.S. state of Kansas. Its county seat is Johnson City. As of the 2020 census, the county population was 2,084. It was named for Edwin Stanton, the U.S. Secretary of War during most of the American Civil War.

K-27 is an approximately 226-mile-long (364 km) north–south state highway that parallels Kansas' western border with Colorado. It is the westernmost north–south state highway in the state. It begins at U.S. Route 56 (US-56) in Elkhart near the Oklahoma state line and travels through the seven counties that border Colorado until reaching its northern terminus north of St. Francis, where it ends at the Nebraska state line. Along the way, it intersects several major highways, including US-160 in Johnson City, US-50 and US-400 in Syracuse, US-40 in Sharon Springs, Interstate 70 (I-70) and US-24 in Goodland, and US-36 in Wheeler. The section from US-40 north to Nebraska, is designated as the Land and Sky Scenic Byway. K-27 changes time zones twice, during its trek through Kansas, the only highway in the state to do so.