Strange Interlude is an experimental play in nine acts by American playwright Eugene O'Neill. It won the 1928 Pulitzer Prize for Drama. Strange Interlude is one of the few modern plays to make extensive use of a soliloquy technique, in which the characters speak their inner thoughts to the audience.

Eugene Gladstone O'Neill was an American playwright. His poetically titled plays were among the first to introduce into the U.S. the drama techniques of realism, earlier associated with Chekhov, Ibsen, and Strindberg. The tragedy Long Day's Journey into Night is often included on lists of the finest U.S. plays in the 20th century, alongside Tennessee Williams's A Streetcar Named Desire and Arthur Miller's Death of a Salesman. He was awarded the 1936 Nobel Prize in Literature. O'Neill is also the only playwright to win four Pulitzer Prizes for Drama.