Tabora Region is one of Tanzania's 31 administrative regions. The regional capital is the municipality of Tabora. The region is located in mid-western part of Tanzania. Tabora is bordered by Shinyanga to the north, Singida to the east, Mbeya and Songwe to the south. lastly, Katavi, Kigoma and Geita, border Tabora to the west. Tabora is by far the largest region in Tanzania by area. Most of the population in the region is concentrated in the north in Nzega district. According to the 2022 national census, Tabora Region had a population of 3,391,679.

Tabora is the capital of Tanzania's Tabora Region and is classified as a municipality by the Tanzanian government. It is also the administrative seat of Tabora Urban District. According to the 2012 census, the district had a population of 226,999.