Tahlequah is a city in Cherokee County, Oklahoma located at the foothills of the Ozark Mountains. It is part of the Green Country region of Oklahoma and was established as a capital of the 19th-century Cherokee Nation in 1839, as part of the new settlement in Indian Territory after the Cherokee Native Americans were forced west from the American Southeast on the Trail of Tears.

Cherokee or Tsalagi is an endangered-to-moribund Iroquoian language and the native language of the Cherokee people. Ethnologue states that there were 1,520 Cherokee speakers out of 376,000 Cherokees in 2018, while a tally by the three Cherokee tribes in 2019 recorded about 2,100 speakers. The number of speakers is in decline. The Tahlequah Daily Press reported in 2019 that most speakers are elderly, about eight fluent speakers die each month, and that only 5 people under the age of 50 are fluent. The dialect of Cherokee in Oklahoma is "definitely endangered", and the one in North Carolina is "severely endangered" according to UNESCO. The Lower dialect, formerly spoken on the South Carolina–Georgia border, has been extinct since about 1900. The dire situation regarding the future of the two remaining dialects prompted the Tri-Council of Cherokee tribes to declare a state of emergency in June 2019, with a call to enhance revitalization efforts.