Tessarakonteres, or simply "forty", was a very large catamaran galley reportedly built in the Hellenistic period by Ptolemy IV Philopator of Egypt. It was described by a number of ancient sources, including a lost work by Callixenus of Rhodes and surviving texts by Athenaeus and Plutarch. According to these descriptions, supported by modern research by Lionel Casson, the enormous size of the vessel made it impractical and it was built only as a prestige vessel, rather than an effective warship. The name "forty" refers not to the number of oars, but to the number of rowers on each column of oars that propelled it, and at the size described it would have been the largest ship constructed in antiquity, and probably the largest human-powered vessel ever built.

From the 4th century BC on, new types of oared warships appeared in the Mediterranean Sea, superseding the trireme and transforming naval warfare. Ships became increasingly large and heavy, including some of the largest wooden ships hitherto constructed. These developments were spearheaded in the Hellenistic Near East, but also to a large extent shared by the naval powers of the Western Mediterranean, specifically Carthage and the Roman Republic. While the wealthy successor kingdoms in the East built huge warships ("polyremes"), Carthage and Rome, in the intense naval antagonism during the Punic Wars, relied mostly on medium-sized vessels. At the same time, smaller naval powers employed an array of small and fast craft, which were also used by the ubiquitous pirates. Following the establishment of complete Roman hegemony in the Mediterranean after the Battle of Actium, the nascent Roman Empire faced no major naval threats. In the 1st century AD, the larger warships were retained only as flagships and were gradually supplanted by the light liburnians until, by Late Antiquity, the knowledge of their construction had been lost.