The American Mercury was an American magazine published from 1924 to 1981. It was founded as the brainchild of H. L. Mencken and drama critic George Jean Nathan. The magazine featured writing by some of the most important writers in the United States through the 1920s and 1930s.

Henry Louis Mencken was an American journalist, essayist, satirist, cultural critic, and scholar of American English. He commented widely on the social scene, literature, music, prominent politicians, and contemporary movements. His satirical reporting on the Scopes Trial, which he dubbed the "Monkey Trial", also gained him attention. The term Menckenian has entered multiple dictionaries to describe anything of or pertaining to Mencken, including his combative rhetorical and prose style.