The Golden Spiders: A Nero Wolfe Mystery is a 2000 American crime drama television film based on the 1953 novel by Rex Stout. Set in 1950s Manhattan, it stars Maury Chaykin as the heavyweight detective genius Nero Wolfe, and Timothy Hutton as Wolfe's assistant, Archie Goodwin, narrator of the Nero Wolfe stories. Veteran screenwriter Paul Monash adapted the novel, and Bill Duke directed. When it first aired on A&E on March 5, 2000, The Golden Spiders was seen in 3.2 million homes, making it the fourth-most-watched A&E original movie ever. Its success led to the A&E original series A Nero Wolfe Mystery (2001–2002).

Maury Alan Chaykin was an American–Canadian actor, best known for his portrayal of Rex Stout's fictional detective Nero Wolfe in the A&E series A Nero Wolfe Mystery, as well as for his work as a character actor in many films and television programs.