Titusville is a city in and the county seat of Brevard County, Florida, United States. As of the 2020 census, the population of the city was 48,789, up from 43,761 at the 2010 census. Titusville is located along the Indian River, west of Merritt Island and the Kennedy Space Center, and south-southwest of the Canaveral National Seashore. It is a principal city of the Palm Bay–Melbourne–Titusville, Florida Metropolitan Statistical Area.

Brevard County is a county in Central East Florida on the Atlantic coast of the U.S. state of Florida. As of the 2020 census, the population was 606,612, making it the 10th-most populated county in Florida. The official county seat is located in Titusville. Brevard County comprises the Palm Bay–Melbourne–Titusville, FL Metropolitan Statistical Area. It is located along the east Florida coast and bordered by the Atlantic Ocean.