The Tre Valli Varesine is a semi classic European bicycle race held in Varese, Italy. From 2005 to 2019, the race was organised as a 1.HC event on the UCI Europe Tour. In 2021 it joined the UCI ProSeries calendar after being cancelled in 2020.

The classic cycle races are the most prestigious one-day professional road cycling races in the international calendar. Some of these events date back to the 19th century. They are normally held at roughly the same time each year. The five most revered races are often described as the cycling monuments.