The Tyne Valley Line is a 58-mile (93 km) route, linking Newcastle upon Tyne with Hexham and Carlisle, England. The line follows the course of the River Tyne through Tyne and Wear and Northumberland. Five stations and two viaducts on the route are listed structures.

Hexham is a market town and civil parish in Northumberland, England, on the south bank of the River Tyne, formed by the confluence of the North Tyne and the South Tyne at Warden nearby, and close to Hadrian's Wall. Hexham was the administrative centre for the Tynedale district from 1974 to 2009. In 2011, it had a population of 13,097.