Native Americans have made up an integral part of U.S. military conflicts since America's beginning. Colonists recruited Indian allies during such instances as the Pequot War from 1634–1638, the Revolutionary War, as well as in War of 1812. Native Americans also fought on both sides during the American Civil War, as well as military missions abroad including the most notable, the Codetalkers who served in World War II. The Scouts were active in the American West in the late 19th and early 20th centuries. Including those who accompanied General John J. Pershing in 1916 on his expedition to Mexico in pursuit of Pancho Villa. Indian Scouts were officially deactivated in 1947 when their last member retired from the Army at Fort Huachuca, Arizona. For many Indians it was an important form of interaction with European-American culture and their first major encounter with the Whites' way of thinking and doing things.

A code talker was a person employed by the military during wartime to use a little-known language as a means of secret communication. The term is most often used for United States service members during the World Wars who used their knowledge of Native American languages as a basis to transmit coded messages. In particular, there were approximately 400 to 500 Native Americans in the United States Marine Corps whose primary job was to transmit secret tactical messages. Code talkers transmitted messages over military telephone or radio communications nets using formally or informally developed codes built upon their Indigenous languages. The code talkers improved the speed of encryption and decryption of communications in front line operations during World War II and are credited with a number of decisive victories. Their code was never broken.