The University of Houston System is a public university system in the U.S. state of Texas, comprising four separate and distinct universities. It also owns and holds broadcasting licenses to a public television station (KUHT) and a public radio station (KUHF).

A university system is a set of multiple affiliated universities and colleges that are usually geographically distributed. Typically, all member universities in a university system share a common component among all of their various names. Usually, all member universities of a university system are governed by a system-wide governing body, such as a board of trustees or a board of regents. In the United States, many states have one or two state university systems under which many of their publicly funded universities are aligned, both in name and in governance. Additionally, for-profit universities, such as DeVry University, often have multiple campuses which share the same name; these may be, but are not always, described as a university system.