Upper St. Clair High School (USCHS) is a public secondary school in Upper St. Clair, Pennsylvania and the sole high school within the township's namesake school district. Serving students in grades 9–12, USCHS is one of three secondary schools in Pennsylvania to be recognized as a Blue Ribbon School three times.

Upper St. Clair is a township with home rule status in southern Allegheny County, Pennsylvania, United States, located approximately 8 miles (13 km) south of Downtown Pittsburgh. It is known for being an affluent suburb with a nationally recognized school district. As of the 2020 census, the township population was 21,160.