The vice president of Colombia is the second-highest officer in the executive branch of the national government, after the president of Colombia, and ranks first in the presidential line of succession. The vice president is indirectly elected together with the president to a four-year term of office by the people of Colombia through the Popular Vote. Since the passage of the Article 102 Amendment to the Colombian Constitution, the vice president may also be appointed by the president to fill a vacancy, upon leave of absence or death, resignation, or removal of the president. Since the 1990s, the vice president has been afforded an official residence at the Vice Presidential House of Bogotá, D.C.

The President of Colombia is the head of state and head of government of the Republic of Colombia. The president heads the executive branch of the national government and is the commander-in-chief of the Military Forces of Colombia.