Vincenzo Natali is a Canadian film director and screenwriter, known for writing and directing science fiction and horror films such as Cube, Cypher, Nothing, and Splice.

Cube is a 1997 Canadian science fiction horror-thriller film directed and co-written by Vincenzo Natali. A product of the Canadian Film Centre's First Feature Project, Nicole de Boer, Nicky Guadagni, David Hewlett, Andrew Miller, Julian Richings, Wayne Robson, and Maurice Dean Wint star as individuals trapped in a bizarre and deadly labyrinth of cube-shaped rooms.