Virginia State Route 7 (VA 7) is a major primary state highway and busy commuter route in northern Virginia, United States. It travels southeast from downtown Winchester to SR 400 in downtown Alexandria. Its route largely parallels those of the Washington & Old Dominion Trail and the Potomac River. Between its western terminus and Interstate 395 (I-395), SR 7 is part of the National Highway System. In 1968, the Virginia State Highway Commission designated the road as the "Harry Flood Byrd Highway" between Alexandria and Winchester to commemorate Harry F. Byrd Sr. (1887–1966).

Winchester is the northwesternmost independent city in the Commonwealth of Virginia, United States. It is the county seat of Frederick County, although the two are separate jurisdictions. As of the 2020 census, the city's population was 28,120. It is the principal city of the Winchester metropolitan area with a population of just over 145,000 extending into West Virginia, which is a part of the Washington–Baltimore combined statistical area. Winchester is home to Shenandoah University and the Museum of the Shenandoah Valley.