"Wagon Wheel" is a song co-written by Bob Dylan and Ketch Secor of Old Crow Medicine Show. Dylan recorded the chorus in 1973; Secor added verses 25 years later. Old Crow Medicine Show's final version was certified Platinum by the Recording Industry Association of America in April 2013. The song has been covered numerous times, including charting versions by Nathan Carter in 2012 and Darius Rucker in 2013.

Old Crow Medicine Show is an Americana string band based in Nashville, Tennessee, that has been recording since 1998. They were inducted into the Grand Ole Opry on September 17, 2013. Their ninth album, Remedy, released in 2014, won the Grammy Award for Best Folk Album. The group's music has been called old-time, folk, and alternative country. Along with original songs, the band performs many pre-World War II blues and folk songs.