The Walter Reed Army Institute of Research (WRAIR) is the largest biomedical research facility administered by the U.S. Department of Defense (DoD). The institute is centered at the Forest Glen Annex, in the Forest Glen Park part of the unincorporated Silver Spring urban area in Maryland just north of Washington, DC, but it is a subordinate unit of the U.S. Army Medical Research and Development Command (USAMRDC), headquartered at nearby Fort Detrick, Maryland. At Forest Glen, the WRAIR has shared a laboratory and administrative facility — the Sen Daniel K. Inouye Building, also known as Building 503 — with the Naval Medical Research Center since 1999.

Daniel Ken Inouye was an American attorney, soldier, and politician who served as a United States senator from Hawaii from 1963 until his death in 2012. Beginning in 1959, he was the first U.S. Representative for the State of Hawaii, and a Medal of Honor recipient. A member of the Democratic Party, he also served as the president pro tempore of the United States Senate from 2010 until his death. Inouye was the highest-ranking Asian-American politician in U.S. history until Kamala Harris became vice president in 2021. Inouye also chaired various senate committees, including those on Intelligence, Indian Affairs, Commerce, and Appropriations.