Wisteria Lane is the name of a fictional street at the center of U.S. television drama series Desperate Housewives. Desperate Housewives storylines primarily center on the residents of the street. The set for Wisteria Lane is located inside Universal Studios Hollywood, and is actually named Colonial Street, an area that has been used for many motion pictures and television shows. Other film and television productions in which Colonial Street has featured include the original Leave It to Beaver series, Gremlins, The 'Burbs, and Buffy the Vampire Slayer.

Desperate Housewives is an American comedy-drama mystery television series created by Marc Cherry and produced by ABC Studios and Cherry Productions. It aired for eight seasons on ABC from October 3, 2004, until May 13, 2012, for a total of 180 episodes. Executive producer Marc Cherry served as showrunner. Other executive producers since the fourth season included Bob Daily, George W. Perkins, John Pardee, Joey Murphy, David Grossman, and Larry Shaw.