The Yale Political Union (YPU) is a debate society at Yale University, founded in 1934 by Alfred Whitney Griswold. It was modeled on the Cambridge Union and Oxford Union and the party system of the defunct Yale Unions of the late nineteenth and early twentieth centuries, which were in turn inspired by the great literary debating societies of Linonia and Brothers in Unity. Members of the YPU have reciprocal rights at sister societies in England.

Alfred Whitney Griswold was an American historian and educator. He served as 16th president of Yale University from 1951 to 1963, during which he built much of Yale's modern scientific research infrastructure, especially on Science Hill.