Óscar Hernández Pérez is a former professional male tennis player from Spain. He turned pro in 1998 and achieved his career-high singles ranking of World No. 48 in October 2007. Hernández scored an upset in the first round of the 2007 Rome Masters, when he defeated the World No. 20, Lleyton Hewitt, 3–6, 7–6(3), 6–1. Hernández announced his retirement from tennis on 22 July 2011.

Defending champion Roger Federer defeated Andre Agassi in the final, 6–3, 2–6, 7–6(7–1), 6–1 to win the men's singles tennis title at the 2005 US Open. It was his second US Open title and sixth major title overall. This was Agassi's last appearance in a major final.