Özgön or Uzgen is a district of Osh Region in south-western Kyrgyzstan. Its area is 3,308 square kilometres (1,277 sq mi), and its resident population was 282,981 in 2021. The capital lies at Özgön (Uzgen).

Osh Region is a region (oblast) of Kyrgyzstan. Its capital is Osh, which is not part of the region. It is bounded by (clockwise) Jalal-Abad Region, Naryn Region, China (Xinjiang), Tajikistan, Batken Region, and Uzbekistan. Its total area is 28,934 km2 (11,171 sq mi). The resident population of the region was 1,391,649 as of January 2021. The region has a sizeable Uzbek minority.