Ōiso Station is a passenger railway station located in the town of Ōiso, Kanagawa Prefecture, Japan, operated by the East Japan Railway Company.

Ōiso is a town located in Kanagawa Prefecture, Japan. As of 1 January 2023, the town had an estimated population of 31,262 and a population density of 1820 persons per km². The total area of the town is 17.18 square kilometres (6.63 sq mi).