The Şehzade Mosque is a 16th-century Ottoman imperial mosque located in the district of Fatih, on the third hill of Istanbul, Turkey. It was commissioned by Suleiman the Magnificent as a memorial to his son Şehzade Mehmed who died in 1543. It is sometimes referred to as the "Prince's Mosque" in English. The mosque was one of the earliest and most important works of architect Mimar Sinan and is one of the signature works of Classical Ottoman architecture.

Mimar Sinan also known as Koca Mi'mâr Sinân Âğâ, was the chief Ottoman architect, engineer and mathematician for sultans Suleiman the Magnificent, Selim II and Murad III. He was responsible for the construction of more than 300 major structures, including the Selimiye Mosque in Edirne, the Kanuni Sultan Suleiman Bridge in Büyükçekmece, and the Mehmed Paša Sokolović Bridge in Višegrad, as well as other more modest projects such as madrasa's, külliyes, and bridges. His apprentices would later design the Sultan Ahmed Mosque in Istanbul and the Stari Most bridge in Mostar.